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The process of isolating the occupied ingredient, cocaine hydrochloride, was maiden proficient in the mid-19th century. Chemists like Albert Niemann in Germany and Paolo Mantegazza in Italy played vital roles in pioneer investigation and discovery. By the late 1800s, buy cocaine cocaine was being reach-me-down in medical treatments, notably as a municipal anesthetic, and was even promoted about pre-eminent figures like Sigmund Freud, who believed it had therapeutic potential. No matter how, as its addictive properties became apparent, governments began to regulate and eventually criminalize its use about the untimely 20th century.
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